RT Journal Article
SR Electronic
T1 Diabetes mellitus, diabetes insipidus, and optic atrophy. An autosomal recessive syndrome?
JF Journal of Medical Genetics
JO J Med Genet
FD BMJ Publishing Group Ltd
SP 190
OP 193
DO 10.1136/jmg.14.3.190
VO 14
IS 3
A1 Fraser, F C
A1 Gunn, T
YR 1977
UL http://jmg.bmj.com/content/14/3/190.abstract
AB Twenty-one families were selected from the published reports in which the propositus had the triad of juvenile diabetes mellitus, diabetes insipidus, and optic atrophy. The data were consistent with the hypothesis of an autosomal gene which, in the homozygote, causes juvenile diabetes mellitus and one or more of diabetes insipidus, optic atrophy, and nerve deafness. Heterozygotes appear to have an increased probability of developing juvenile diabetes mellitus.